Description
Product Characteristics:
Aliases: bA4204.1 antibody, C20orf31 antibody, C20orf49 antibody, EDEM 2 antibody, EDEM2 antibody, EDEM2_HUMAN antibody, ER degradation enhancer mannosidase alpha like 2 antibody, ER degradation enhancing alpha mannosidase like 2 antibody, ER degradation enhancing alpha mannosidase like protein 2 antibody, ER degradation enhancing mannosidase like protein 2 antibody, ER degradation-enhancing alpha-mannosidase-like 2 antibody, FLJ10783 antibody, UNQ573/PRO1135 antibody
Target Information: In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005 [PubMed 15537790]).[supplied by OMIM, Mar 2008]